PhD students and staff

We have two PhD studentships (one industry funded) soon to be advertised for September 2023 start - link and details to follow. We are looking for self-motivated individuals with an interest to learn about cell-free transcription-translation systems.

Independent funding

We welcome motivated individuals seeking independent funding from UK or international fellowships, studentships or short-term placement schemes. We are particularly keen to support individuals seeking to learn and expand the area of cell-free synthetic biology. In addition, we also welcome self-funded individuals. Please contact Dr Simon Moore at s.j.r.moore[at] for informal discussions.

Masters by research students

We regularly support summer studentships and MSc by research students. Potential projects are listed below.

MSc-R projects available

"Silent" biosynthetic gene clusters

Synthetic biology is accelerating the discovery of promising new bioactive natural products. We are interested in studying "silent" biosynthetic gene clusters and specific pathways of interest. Our focus is on developing tools that overcome barriers in natural product discovery, as well as elucidating biosynthetic pathways.

Novel antibiotics for Gram-negative bacterial infectious diseases

There is an urgent need to develop new antibiotics to prevent mortality from infectious diseases. We are working on new methodologies to identify antibiotics that inhibit Gram-negative bacteria (to be published).

Cell-free TX-TL and biosynthesis

Cell-free TX-TL is a rapidly developing area in synthetic biology for the implementation of the design-built-test-learn cycle. We are interested in the potential of using cell-free systems to study Streptomyces genetics, BGCs and enzymes from natural product biosynthesis.

Fluorescent direct protein (DiPro) biosensors

Fluorescence is a valuable physical property widely exploited for medical imaging through to detecting diseases and toxic chemicals. Recently, we have discovered a novel fluorescent protein that detects specific chemicals. We call this mechanism a direct protein (DiPro) biosensor.

DiPro biosensor preprint -