Cell-Free Gene Expression (CFE) Systems

Cell-free gene expression systems provide a bottom-up approach for synthetic biology engineering. The Moore group specialises in developing novel cell-free systems in different bacterial systems for specific applications. We have expertise, protocols, extracts and plasmid expression systems for the following bacteria:


  • Escherichia coli (BL21, Rosetta, MG1655)

  • Bacillus megaterium

  • Streptomyces spp., including Streptomyces venezuelae

  • New systems (Gram-negative, Gram-positive) in development


We collaborate with a range of academic groups and industry both from within the UK and internationally.

  • For expressions of interest, feel free to email Dr Simon Moore at simon.moore[at]qmul.ac.uk